Therapy Detail
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| Therapy Name | Cetrelimab + JNJ-87704916 |
| Synonyms | |
| Therapy Description | |
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| Drug Name | Trade Name | Synonyms | Drug Classes | Drug Description |
|---|---|---|---|---|
| Cetrelimab | JNJ63723283|JNJ 63723283|JNJ-63723283 | Immune Checkpoint Inhibitor 150 PD-L1/PD-1 antibody 132 | Cetrelimab (JNJ-63723283) is a monoclonal antibody that targets PD-1 (PDCD1) and inhibits binding of the PD-L1 (CD274) ligand, potentially resulting in enhanced anti-tumor immune response (PMID: 28943093). | |
| JNJ-87704916 | JNJ87704916|JNJ 87704916 | JNJ-87704916 is a recombinant oncolytic herpes simplex virus type 1 (HSV-1), which potentially induces tumor cell lysis and an antitumor immune response (NCI Drug Dictionary). |
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| Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
|---|
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| Clinical Trial | Phase | Therapies | Title | Recruitment Status | Covered Countries | Other Countries |
|---|---|---|---|---|---|---|
| NCT06311578 | Phase I | JNJ-87704916 Cetrelimab + JNJ-87704916 | A Study of JNJ-87704916, as Monotherapy and in Combination for Advanced Solid Tumors | Recruiting | USA | FRA | ESP | CAN | 0 |
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