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Drug Name | Cetrelimab |
Trade Name | |
Synonyms | JNJ63723283|JNJ 63723283|JNJ-63723283 |
Drug Descriptions |
Cetrelimab (JNJ-63723283) is a monoclonal antibody that targets PD-1 (PDCD1) and inhibits binding of the PD-L1 (CD274) ligand, potentially resulting in enhanced anti-tumor immune response (PMID: 28943093). |
DrugClasses | Immune Checkpoint Inhibitor 149 PD-L1/PD-1 antibody 121 |
CAS Registry Number | 2050478-92-5 |
NCIT ID | C129448 |
Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
---|---|---|---|
Amivantamab-vmjw + Cetrelimab | Amivantamab-vmjw Cetrelimab | 0 | 1 |
Apalutamide + Cetrelimab | Apalutamide Cetrelimab | 0 | 2 |
Cabazitaxel + Carboplatin + Cetrelimab | Cabazitaxel Carboplatin Cetrelimab | 0 | 1 |
Cetrelimab | Cetrelimab | 0 | 2 |
Cetrelimab + Daratumumab | Cetrelimab Daratumumab | 0 | 1 |
Cetrelimab + Erdafitinib | Cetrelimab Erdafitinib | 2 | 2 |
Cetrelimab + JNJ-78278343 | Cetrelimab JNJ-78278343 | 0 | 1 |
Cetrelimab + JNJ-86974680 | Cetrelimab JNJ-86974680 | 0 | 1 |
Cetrelimab + JNJ-87704916 | Cetrelimab JNJ-87704916 | 0 | 1 |
Cetrelimab + Niraparib | Cetrelimab Niraparib | 0 | 2 |
Cetrelimab + TAR-200 | Cetrelimab TAR-200 | 0 | 4 |