Therapy Detail
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| Therapy Name | XmAb541 |
| Synonyms | |
| Therapy Description |
XmAb541 is a bispecific antibody targeting CLDN6 and CD3 that redirects cytotoxic T-lymphocytes towards tumor cells expressing CLDN6, potentially resulting in increased tumor cell killing (J Clin Oncol 2025 43: 5_suppl, TPS652, NCI Drug Dictionary). |
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| Drug Name | Trade Name | Synonyms | Drug Classes | Drug Description |
|---|---|---|---|---|
| XmAb541 | XmAb-541|XmAb 541 | CD3 Antibody 119 CLDN6 Antibody 10 | XmAb541 is a bispecific antibody targeting CLDN6 and CD3 that redirects cytotoxic T-lymphocytes towards tumor cells expressing CLDN6, potentially resulting in increased tumor cell killing (J Clin Oncol 2025 43: 5_suppl, TPS652, NCI Drug Dictionary). |
Filtering
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- Use simple literal full or partial string matches
- Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
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- Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")
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| Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
|---|
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- Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")
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- Click on any column header arrows to sort by that column
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| Clinical Trial | Phase | Therapies | Title | Recruitment Status | Covered Countries | Other Countries |
|---|---|---|---|---|---|---|
| NCT06276491 | Phase I | XmAb541 | Phase 1, Safety and Tolerability Study of XmAb®541 in Advanced Solid Tumors | Recruiting | USA | 0 |
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