Therapy Detail
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| Therapy Name | TSC-204-A0201 |
| Synonyms | |
| Therapy Description |
TSC-204-A0201 comprises autologous T-cells engineered to express a T-cell receptor (TCR) targeting the MAGE-A1 antigen presented on HLA-A*02:01, which potentially induce cytotoxic T-lymphocyte (CTL)-dependent killing of MAGE-A1-expressing tumor cells (NCI Drug Dictionary). |
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| Drug Name | Trade Name | Synonyms | Drug Classes | Drug Description |
|---|---|---|---|---|
| TSC-204-A0201 | TSC 204-A0201|TSC204-A0201 | TSC-204-A0201 comprises autologous T-cells engineered to express a T-cell receptor (TCR) targeting the MAGE-A1 antigen presented on HLA-A*02:01, which potentially induce cytotoxic T-lymphocyte (CTL)-dependent killing of MAGE-A1-expressing tumor cells (NCI Drug Dictionary). |
Filtering
- Case insensitive filtering will display rows if any text in any cell matches the filter term
- Use simple literal full or partial string matches
- Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
- Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
- Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")
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| Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
|---|
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- Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
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- Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")
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- Click on any column header arrows to sort by that column
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| Clinical Trial | Phase | Therapies | Title | Recruitment Status | Covered Countries | Other Countries |
|---|---|---|---|---|---|---|
| NCT05973487 | Phase I | TSC-200-A0201 + TSC-204-C0702 TSC-203-A0201 TSC-201-B0702 + TSC-204-A0201 TSC-200-A0201 TSC-204-A0101 + TSC-204-A0201 TSC-201-B0702 TSC-201-B0702 + TSC-204-C0702 TSC-204-A0101 TSC-204-A0101 + TSC-204-C0702 TSC-204-A0201 + TSC-204-C0702 TSC-200-A0201 + TSC-204-A0201 TSC-204-C0702 TSC-203-A0201 + TSC-204-C0702 TSC-204-A0201 TSC-203-A0201 + TSC-204-A0201 TSC-201-B0702 + TSC-204-A0101 TSC-201-B0702 + TSC-203-A0201 TSC-200-A0201 + TSC-204-A0101 TSC-200-A0201 + TSC-203-A0201 TSC-203-A0201 + TSC-204-A0101 TSC-200-A0201 + TSC-201-B0702 | A Basket Study of Customized Autologous TCR-T Cell Therapies in Patients With Locally Advanced (Unresectable) or Metastatic Solid Tumors | Recruiting | USA | 0 |
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