Therapy Detail
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| Therapy Name | JNJ-75348780 + JNJ-80948543 |
| Synonyms | |
| Therapy Description | |
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| Drug Name | Trade Name | Synonyms | Drug Classes | Drug Description |
|---|---|---|---|---|
| JNJ-75348780 | CD3 Antibody 119 | JNJ-75348780 is a bi-specific antibody targeting CD3 and CD22, which may lead to cytotoxic immune response against B-cell tumors (NCI Thesaurus). | ||
| JNJ-80948543 | JNJ 80948543|JNJ80948543 | CD3 Antibody 119 | JNJ-80948543 is an antibody that targets an undisclosed tumor-associated antigen (TAA) and the T-cell antigen CD3, potentially resulting in activation of cytotoxic T-lymphocytes (CTLs) and tumor cell killing (NCI Drug Dictionary). |
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| Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
|---|
Filtering
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- Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")
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| Clinical Trial | Phase | Therapies | Title | Recruitment Status | Covered Countries | Other Countries |
|---|---|---|---|---|---|---|
| NCT06660563 | Phase I | JNJ-75348780 + JNJ-80948543 | A Study of JNJ-80948543 in Combination With Other CD3 T-Cell Engagers in Participants With Relapsed/Refractory B-Cell Non-Hodgkin Lymphoma (R/R B-Cell NHL) | Active, not recruiting | GBR | ESP | AUS | 1 |
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