Therapy Detail
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| Therapy Name | Lanreotide acetate + Lutetium Lu 177 dotatate |
| Synonyms | |
| Therapy Description | |
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| Drug Name | Trade Name | Synonyms | Drug Classes | Drug Description |
|---|---|---|---|---|
| Lanreotide acetate | Somatuline Depot | Lantreotide depot|AT-1001 | Somatuline Depot (lantreotide acetate) is a somatostatin analog peptide-based drug, which may decrease growth of neuroendocrine tumors (PMID: 27619395, PMID: 25014687). Somatuline Depot (lantreotide acetate) is FDA approved for use in gastroenteropancreatic neuroendocrine tumors (FDA.gov). | |
| Lutetium Lu 177 dotatate | Lutathera | LuTate|177Lu-Octreotate|177 Lu-DOTA-Tyr3-octreotate|177Lu-DOTATATE | Lutathera (lutetium Lu 177 dotatate) is a radiolabeled somatostatin analog that may selectively kill somatostatin receptor-positive tumor cells (PMID: 28076709). Lutathera (lutetium Lu 177 dotatate) is FDA approved for use in patients with somatostatin receptor-positive gastroenteropancreatic neuroendocrine tumors (FDA.gov). |
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| Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
|---|
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| Clinical Trial | Phase | Therapies | Title | Recruitment Status | Covered Countries | Other Countries |
|---|---|---|---|---|---|---|
| NCT06878664 | Phase III | Lutetium Lu 177 dotatate + Octreotide acetate Lanreotide acetate + Lutetium Lu 177 dotatate | Randomized Interval Assessment Trial of Lu177-Dotatate in Slowly Progressive G1-2 Advanced Midgut Neuroendocrine Tumors (RIALTO) | Recruiting | FRA | ESP | 0 |
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