Therapy Detail
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| Therapy Name | MORAb-202 + Prednisone |
| Synonyms | |
| Therapy Description | |
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| Drug Name | Trade Name | Synonyms | Drug Classes | Drug Description |
|---|---|---|---|---|
| MORAb-202 | MORAb 202|MORAb202 | FOLR1-targeted Therapy 24 | MORAb-202 is an anti-folate receptor alpha (FRA) antibody (farletuzumab) in conjugation with eribulin, which may lead to cytotoxic killing of FRA-positive tumors (Mol Cancer Ther 2018;17(1 Suppl):Abstract nr B115, PMID: 30262588). | |
| Prednisone | Adasone | Dehydrocortisone | Adasone (prednisone) is a corticosteroid which functions as an immunosuppressant and anti-inflammatory agent and which may stimulate apoptosis in tumor cells (NCI Drug Dictionary). |
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| Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
|---|
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| Clinical Trial | Phase | Therapies | Title | Recruitment Status | Covered Countries | Other Countries |
|---|---|---|---|---|---|---|
| NCT04300556 | Phase Ib/II | Dexamethasone + MORAb-202 MORAb-202 + Prednisolone MORAb-202 + Prednisone Lenvatinib + MORAb-202 MORAb-202 | A Study to Evaluate the Safety, Tolerability, and Efficacy of MORAb-202 (Herein Referred to as Farletuzumab Ecteribulin), a Folate Receptor Alpha (FRalph)-Targeting Antibody-drug Conjugate (ADC) in Participants With Selected Tumor Types | Recruiting | USA | GBR | FRA | ESP | 1 |
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