Therapy Detail
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| Therapy Name | JNJ-64457107 + PGG beta-glucan |
| Synonyms | |
| Therapy Description | |
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| Drug Name | Trade Name | Synonyms | Drug Classes | Drug Description |
|---|---|---|---|---|
| JNJ-64457107 | ADC-1013|Mitazalimab|JNJ 7107 | CD40 Antibody 16 | JNJ-64457107 (mitazalimab) is a CD40 agonist that may lead to a T-cell dependent antitumor response, potentially resulting in tumor growth inhibition (PMID: 25316820, PMID: 30664811). | |
| PGG beta-glucan | Imprime PGG|Odetiglucan | Imprime PGG (PGG beta-glucan) binds to and promotes cytotoxicity of neutrophils bound to tumor cells via complement receptor 3 (CR3) (NCI Drug Dictionary). |
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| Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
|---|
Filtering
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- Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
- Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
- Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")
Sorting
- Generally, the default sort order for tables is set to be first column ascending; however, specific tables may set a different default sort order.
- Click on any column header arrows to sort by that column
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| Clinical Trial | Phase | Therapies | Title | Recruitment Status | Covered Countries | Other Countries |
|---|---|---|---|---|---|---|
| NCT07199764 | Phase II | JNJ-64457107 + PGG beta-glucan | Maintenance Combinatorial Myeloid Immunotherapy for Unresectable Pancreatic Cancer (IGNITE) | Recruiting | USA | 0 |
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