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Drug Name | JNJ-64457107 |
Trade Name | |
Synonyms | ADC-1013|Mitazalimab|JNJ 7107 |
Drug Descriptions |
JNJ-64457107 (mitazalimab) is a CD40 agonist that may lead to a T-cell dependent antitumor response, potentially resulting in tumor growth inhibition (PMID: 25316820, PMID: 30664811). |
DrugClasses | CD40 Antibody 14 |
CAS Registry Number | 2055640-86-1 |
NCIT ID | C121538 |
Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
---|---|---|---|
Fluorouracil + Irinotecan + JNJ-64457107 + Leucovorin + Oxaliplatin | Fluorouracil Irinotecan JNJ-64457107 Leucovorin Oxaliplatin | 0 | 1 |
JNJ-64457107 | JNJ-64457107 | 0 | 2 |