Therapy Detail
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| Therapy Name | AZD9574 + FPI-2265 |
| Synonyms | |
| Therapy Description | |
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| Drug Name | Trade Name | Synonyms | Drug Classes | Drug Description |
|---|---|---|---|---|
| AZD9574 | AZD-9574|AZD 9574 | PARP-1 Inhibitor 13 | AZD9574 is a PARP1 inhibitor that can penetrate the blood-brain barrier, potentially leading to inhibition of tumor growth (PMID: 37967136). | |
| FPI-2265 | FPI 2265|FPI2265|225Ac-PSMA-I&T | FPI-2265 is a radioconjugate comprising the radionuclide actinium-225 linked to a monoclonal antibody that targets PSMA, which delivers radiation to PSMA-expressing tumor cells, potentially resulting in antitumor activity (Cancer Res (2024) 84 (7_Supplement): CT224). |
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| Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
|---|
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- Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")
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| Clinical Trial | Phase | Therapies | Title | Recruitment Status | Covered Countries | Other Countries |
|---|---|---|---|---|---|---|
| NCT07590934 | Phase Ib/II | FPI-2265 AZD9574 + FPI-2265 Docetaxel | Phase Ib/II Platform Study of Multiple Anti-Cancer Agents in Participants With Metastatic Prostate Cancer (PROSPECTOR) | Not yet recruiting | USA | ITA | GBR | ESP | DEU | AUS | 1 |
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