Therapy Detail
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| Therapy Name | BMS-986340 + BNT327 |
| Synonyms | |
| Therapy Description | |
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| Drug Name | Trade Name | Synonyms | Drug Classes | Drug Description |
|---|---|---|---|---|
| BMS-986340 | BMS 986340|BMS986340 | CCR8 Antibody 13 | BMS-986340 is a nonfucosylated monoclonal antibody that targets CCR8, with potential antitumor activity and ability to enhance antitumor immune response (Cancer Res 2020;80(16 Suppl):Abstract nr 6694). | |
| BNT327 | PM8002|Pumitamig|BNT-327|BNT 327|BM-8002 | PD-L1/PD-1 antibody 138 VEGFA Antibody 6 | BNT327 (PM8002) is a bispecific antibody that targets VEGFA and PD-L1 (CD274), which potentially induces antitumor activity (J Clin Oncol 42, no. 16_suppl (May 29, 2024) 5524). |
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| Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
|---|
Filtering
- Case insensitive filtering will display rows if any text in any cell matches the filter term
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- Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
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- Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")
Sorting
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| Clinical Trial | Phase | Therapies | Title | Recruitment Status | Covered Countries | Other Countries |
|---|---|---|---|---|---|---|
| NCT04895709 | Phase Ib/II | BMS-986340 + Docetaxel BMS-986340 + BNT327 BMS-986340 BMS-986340 + Nivolumab | A Study of BMS-986340 as Monotherapy and as Combination Therapy in Participants With Advanced Solid Tumors | Recruiting | USA | ITA | ISR | ESP | DEU | CAN | AUS | 1 |
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