Therapy Detail
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| Therapy Name | CT-202 |
| Synonyms | |
| Therapy Description |
CT-202 is a humanized, dual pH-dependent bispecific T-cell engager that selectively targets NECTIN4 and CD3 in the acidic tumor microenvironment, which potentially induces T cell-mediated cytotoxicity against tumor cells (Cancer Res (2026) 86 (7_Supplement): 5392). |
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| Drug Name | Trade Name | Synonyms | Drug Classes | Drug Description |
|---|---|---|---|---|
| CT-202 | CT202|CT 202 | CD3 Antibody 128 NECTIN4 Antibody 14 | CT-202 is a humanized, dual pH-dependent bispecific T-cell engager that selectively targets NECTIN4 and CD3 in the acidic tumor microenvironment, which potentially induces T cell-mediated cytotoxicity against tumor cells (Cancer Res (2026) 86 (7_Supplement): 5392). |
Filtering
- Case insensitive filtering will display rows if any text in any cell matches the filter term
- Use simple literal full or partial string matches
- Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
- Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
- Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")
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| Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
|---|
Filtering
- Case insensitive filtering will display rows if any text in any cell matches the filter term
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- Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
- Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
- Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")
Sorting
- Generally, the default sort order for tables is set to be first column ascending; however, specific tables may set a different default sort order.
- Click on any column header arrows to sort by that column
- Hold down the Shift key and click multiple columns to sort by more than one column. Be sure to set ascending or descending order for a given column before moving on to the next column.
| Clinical Trial | Phase | Therapies | Title | Recruitment Status | Covered Countries | Other Countries |
|---|---|---|---|---|---|---|
| NCT07545122 | Phase I | CT-202 | A Phase 1a/1b, First-Time-in-Human Study of CT-202, a Nectin-4 Directed Bispecific Antibody, in Participants With Recurring Triple Negative Breast, Colorectal, Urothelial Cancers (CT-202) | Not yet recruiting | AUS | 0 |
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