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Therapy Name | SGT-53 |
Synonyms | |
Therapy Description |
SGT-53 is a cationic liposomal complex that is linked to an antibody targeting the transferrin receptor (Tff) and contains wild-type Tp53 plasmid, thereby delivering wild-type Tp53 to tumor cells expressing Tff and potentially restoring wild-type Tp53 activity (PMID: 23470564, PMID: 27357628, PMID: 31241175) |