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Therapy Name | Cergutuzumab amunaleukin |
Synonyms | |
Therapy Description |
Cergutuzumab amunaleukin (RG7813) is a bispecific antibody that binds carcinoembyronic antigen (CEA) and CD3, potentially resulting in enhanced T-cell response to CEA-expresssing tumor cells (European Journal of Cancer, Volume 51, Supplement 1, March 2015, Page S13, PMID: 28405498). |
Drug Name | Trade Name | Synonyms | Drug Classes | Drug Description |
---|---|---|---|---|
Cergutuzumab amunaleukin | RO6895882|RG7813|CEA TCB|RG-7813 | CD3 Antibody 99 | Cergutuzumab amunaleukin (RG7813) is a bispecific antibody that binds carcinoembyronic antigen (CEA) and CD3, potentially resulting in enhanced T-cell response to CEA-expresssing tumor cells (European Journal of Cancer, Volume 51, Supplement 1, March 2015, Page S13, PMID: 28405498). |
Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
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Clinical Trial | Phase | Therapies | Title | Recruitment Status | Covered Countries | Other Countries |
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NCT02004106 | Phase I | Cergutuzumab amunaleukin | A Study of RO6895882 in Patients With Advanced and/or Metastatic Solid Tumors | Completed | USA | NLD | GBR | FRA | FIN | ESP | DNK | CHE | 0 |
NCT02350673 | Phase I | Cergutuzumab amunaleukin Atezolizumab | A Study of Intravenous RO6895882 and MPDL3280A Combination in Patients With Locally Advanced and/or Metastatic Solid Tumors | Completed | USA | NLD | ESP | DNK | CHE | CAN | 0 |