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Therapy Name VAL-083
Synonyms
Therapy Description

Dianhydrogalactitol (VAL-083) is a DNA cross-linking agent which has shown anti-tumor activities in clinical settings (Journal of Clinical Oncology 36, no. 15_suppl., PMID: 6784907).

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Drug Name Trade Name Synonyms Drug Classes Drug Description
VAL-083 Dianhydrogalactitol|VAL083|VAL 083 Dianhydrogalactitol (VAL-083) is a DNA cross-linking agent which has shown anti-tumor activities in clinical settings (Journal of Clinical Oncology 36, no. 15_suppl., PMID: 6784907).

Filtering

  • Case insensitive filtering will display rows if any text in any cell matches the filter term
  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

  • Generally, the default sort order for tables is set to be first column ascending; however, specific tables may set a different default sort order.
  • Click on any column header arrows to sort by that column
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Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References

Filtering

  • Case insensitive filtering will display rows if any text in any cell matches the filter term
  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

  • Generally, the default sort order for tables is set to be first column ascending; however, specific tables may set a different default sort order.
  • Click on any column header arrows to sort by that column
  • Hold down the Shift key and click multiple columns to sort by more than one column. Be sure to set ascending or descending order for a given column before moving on to the next column.

Clinical Trial Phase Therapies Title Recruitment Status Covered Countries Other Countries
NCT01478178 Phase Ib/II VAL-083 Safety Study of VAL-083 in Patients With Recurrent Malignant Glioma or Progressive Secondary Brain Tumor Completed USA 0
NCT03970447 Phase II VAL-083 ADI-PEG 20 AZD1390 VT1021 Lomustine Regorafenib Temozolomide GDC-0084 A Trial to Evaluate Multiple Regimens in Newly Diagnosed and Recurrent Glioblastoma (GBM AGILE) Recruiting USA | FRA | DEU | CHE | CAN | AUS 0
NCT02717962 Phase II VAL-083 Study of VAL-083 in Patients With MGMT Unmethylated, Bevacizumab-naive Recurrent Glioblastoma Completed USA 0


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