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Therapy Detail
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| Therapy Name | INCAGN01949 |
| Synonyms | |
| Therapy Description |
INCAGN01949 is an agonistic monoclonal antibody that targets TNFRSF4 (OX40, CD134), potentially resulting in increased T-lymphocyte proliferation and enhanced antitumor immune response (PMID: 36316061). |
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| Drug Name | Trade Name | Synonyms | Drug Classes | Drug Description |
|---|---|---|---|---|
| INCAGN01949 | INCAGN1949|INCAGN 1949|INCAGN-1949 | OX40 Antibody 14 | INCAGN01949 is an agonistic monoclonal antibody that targets TNFRSF4 (OX40, CD134), potentially resulting in increased T-lymphocyte proliferation and enhanced antitumor immune response (PMID: 36316061). |
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| Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
|---|
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| Clinical Trial | Phase | Therapies | Title | Recruitment Status | Covered Countries | Other Countries |
|---|---|---|---|---|---|---|
| NCT02923349 | Phase Ib/II | INCAGN01949 | A Phase 1/2, Open-Label, Dose-Escalation, Safety Study of INCAGN01949 in Subjects With Advanced or Metastatic Solid Tumors | Completed | USA | GBR | ESP | CHE | 0 |
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