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Therapy Name | BMX-001 + Cisplatin |
Synonyms | |
Therapy Description | |
Drug Name | Trade Name | Synonyms | Drug Classes | Drug Description |
---|---|---|---|---|
BMX-001 | BMX-001 is a human mitochondrial manganese superoxide dismutase (MnSOD) mimetic that clears reactive oxygen species upon cellular internalization, thereby potentially reducing the degree of chemotoxicity within healthy tissue (PMID: 29464912). | |||
Cisplatin | Platinol | CDDP | Chemotherapy - Platinum 7 | Platinol (cisplatin) is a platinum based chemotherapeutic, which is FDA approved for bladder, ovarian, and testicular cancers (NCI Drug Dictionary). |
Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
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Clinical Trial | Phase | Therapies | Title | Recruitment Status | Covered Countries | Other Countries |
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NCT02990468 | Phase I | BMX-001 + Cisplatin | A Trial of Concurrent Radiation Therapy, Cisplatin, and BMX-001 in Locally Advanced Head and Neck Cancer (BMX-HN) | Completed | USA | 0 |