Therapy Detail
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| Therapy Name | ABBV-321 |
| Synonyms | |
| Therapy Description |
ABBV-321 (serclutamab talirine) is an antibody-drug conjugate (ADC) consisting of a monoclonal EGFR antibody and the cytotoxic agent, pyrrolobenzodiazepine, which may lead to inhibition of tumor growth (PMID: 32847977). |
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| Drug Name | Trade Name | Synonyms | Drug Classes | Drug Description |
|---|---|---|---|---|
| ABBV-321 | ABBV321|ABBV 321|Serclutamab talirine | EGFR Antibody 72 | ABBV-321 (serclutamab talirine) is an antibody-drug conjugate (ADC) consisting of a monoclonal EGFR antibody and the cytotoxic agent, pyrrolobenzodiazepine, which may lead to inhibition of tumor growth (PMID: 32847977). |
Filtering
- Case insensitive filtering will display rows if any text in any cell matches the filter term
- Use simple literal full or partial string matches
- Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
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- Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")
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| Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
|---|
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- Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
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- Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")
Sorting
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- Click on any column header arrows to sort by that column
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| Clinical Trial | Phase | Therapies | Title | Recruitment Status | Covered Countries | Other Countries |
|---|---|---|---|---|---|---|
| NCT03234712 | Phase I | ABBV-321 | A Study Evaluating the Safety, Pharmacokinetics, and Anti-tumor Activity of ABBV-321 in Subjects With Advanced Solid Tumors Associated With Overexpression of the Epidermal Growth Factor Receptor (EGFR) or Its Ligands | Completed | USA | ISR | AUS | 0 |
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