Welcome to CKB CORE's new home! Please be sure to update any bookmarks you may have.
×

Drug Detail

Contact

Missing content? – Request curation!

Request curation for specific Genes, Variants, or PubMed publications.

Have questions, comments, or suggestions? - Let us know!

Email us at : ckbsupport@genomenon.com

Drug Name ABBV-321
Trade Name
Synonyms ABBV321|ABBV 321|Serclutamab talirine
Drug Descriptions

ABBV-321 (serclutamab talirine) is an antibody-drug conjugate (ADC) consisting of a monoclonal EGFR antibody and the cytotoxic agent, pyrrolobenzodiazepine, which may lead to inhibition of tumor growth (PMID: 32847977).

DrugClasses EGFR Antibody 58
CAS Registry Number 2140174-56-5
NCIT ID C150590

Filtering

  • Case insensitive filtering will display rows if any text in any cell matches the filter term
  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

  • Generally, the default sort order for tables is set to be first column ascending; however, specific tables may set a different default sort order.
  • Click on any column header arrows to sort by that column
  • Hold down the Shift key and click multiple columns to sort by more than one column. Be sure to set ascending or descending order for a given column before moving on to the next column.

Therapy Name Drugs Efficacy Evidence Clinical Trials
ABBV-321 ABBV-321 0 1
ABBV-321 + Depatuxizumab mafodotin ABBV-321 Depatuxizumab mafodotin 0 0


Additional content available in CKB BOOST