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Therapy Name Axatilimab
Synonyms
Therapy Description

Axatilimab (SNDX-6352) is a humanized monoclonal antibody against colony-stimulating factor-1 receptor (CSF-1R), which may enhance anti-tumor immune response (SITC Meeting, Nov 2017, abstract P505).

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Drug Name Trade Name Synonyms Drug Classes Drug Description
Axatilimab Niktimvo SNDX 6352|SNDX6352|UCB6352|SNDX-6352 CSF1R Antibody 5 Niktimvo (axatilimab) is a humanized monoclonal antibody against colony-stimulating factor-1 receptor (CSF-1R), which may enhance anti-tumor immune response (SITC Meeting, Nov 2017, abstract P505). Niktimvo (axatilimab) is FDA-approved for the treatment of chronic graft-versus-host disease (FDA.gov)

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Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References

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  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
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  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

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  • Generally, the default sort order for tables is set to be first column ascending; however, specific tables may set a different default sort order.
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Clinical Trial Phase Therapies Title Recruitment Status Covered Countries Other Countries
NCT06523556 Phase Ib/II Axatilimab Axatilimab + Azacitidine Axatilimab With or Without Azacitidine for the Treatment of Patients With Advanced Phase Myeloproliferative Neoplasms, Myeloproliferative Neoplasm/Myelodysplastic Syndrome Overlap or High Risk Chronic Myelomonocytic Leukemia Recruiting USA 0
NCT03238027 Phase I Axatilimab Axatilimab + Durvalumab A Phase 1, Open-label, Dose Escalation Trial to Investigate SNDX-6352 in Patients With Solid Tumors Completed USA 0


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