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Drug Name Axatilimab
Trade Name Niktimvo
Synonyms SNDX 6352|SNDX6352|UCB6352|SNDX-6352
Drug Descriptions

Niktimvo (axatilimab) is a humanized monoclonal antibody against colony-stimulating factor-1 receptor (CSF-1R), which may enhance anti-tumor immune response (SITC Meeting, Nov 2017, abstract P505). Niktimvo (axatilimab) is FDA-approved for the treatment of chronic graft-versus-host disease (FDA.gov)

DrugClasses CSF1R Antibody 5
CAS Registry Number 2155851-88-8
NCIT ID C155813

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Therapy Name Drugs Efficacy Evidence Clinical Trials
Axatilimab Axatilimab 0 2
Axatilimab + Azacitidine Axatilimab Azacitidine 0 1
Axatilimab + Durvalumab Axatilimab Durvalumab 0 2
Axatilimab + Nivolumab Axatilimab Nivolumab 0 1
Axatilimab + Olaparib Axatilimab Olaparib 0 1
Axatilimab + Paclitaxel + Retifanlimab Axatilimab Paclitaxel Retifanlimab 0 1
Axatilimab + Pembrolizumab Axatilimab Pembrolizumab 0 1


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