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Therapy Name CLR 131
Synonyms
Therapy Description

CLR 131 is a compound that contains specific phospholipid ethers, CLR 1404, linked to the radioisotope iodine I 131, which when taken up by cancer cells induces cytotoxicity (PMID: 32483729).

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Drug Name Trade Name Synonyms Drug Classes Drug Description
CLR 131 CLR 1404 I-131 CLR 131 is a compound that contains specific phospholipid ethers, CLR 1404, linked to the radioisotope iodine I 131, which when taken up by cancer cells induces cytotoxicity (PMID: 32483729).

Filtering

  • Case insensitive filtering will display rows if any text in any cell matches the filter term
  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

  • Generally, the default sort order for tables is set to be first column ascending; however, specific tables may set a different default sort order.
  • Click on any column header arrows to sort by that column
  • Hold down the Shift key and click multiple columns to sort by more than one column. Be sure to set ascending or descending order for a given column before moving on to the next column.

Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References

Filtering

  • Case insensitive filtering will display rows if any text in any cell matches the filter term
  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

  • Generally, the default sort order for tables is set to be first column ascending; however, specific tables may set a different default sort order.
  • Click on any column header arrows to sort by that column
  • Hold down the Shift key and click multiple columns to sort by more than one column. Be sure to set ascending or descending order for a given column before moving on to the next column.

Clinical Trial Phase Therapies Title Recruitment Status Covered Countries Other Countries
NCT03478462 Phase I CLR 131 Dose Escalation Study of CLR 131 in Children and Adolescents With Relapsed or Refractory Malignant Brain Cancer, Neuroblastoma, Rhabdomyosarcoma, Ewings Sarcoma, and Osteosarcoma Active, not recruiting USA | CAN | AUS 0
NCT04105543 Phase I CLR 131 CLR 131 Combined With Radiation for Head and Neck Cancer Completed USA 0
NCT05610891 Phase I CLR 131 Novel Targeted Radiotherapy in Pediatric Patients With Inoperable Relapsed or Refractory HGG Recruiting USA | CAN 0


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