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Therapy Name BTRC 4017A
Synonyms
Therapy Description

BTRC 4017A is a bispecific antibody that targets both Erbb2 (Her2) and CD3, which may lead to CTL-dependent killing of Erbb2 (Her2)-expressing tumor cells (PMID: 30442682).

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Drug Name Trade Name Synonyms Drug Classes Drug Description
BTRC 4017A BTRC4017A|RG6194|Runimotamab|BTRC-4017A CD3 Antibody 99 HER2 (ERBB2) Antibody 76 BTRC 4017A is a bispecific antibody that targets both Erbb2 (Her2) and CD3, which may lead to CTL-dependent killing of Erbb2 (Her2)-expressing tumor cells (PMID: 30442682).

Filtering

  • Case insensitive filtering will display rows if any text in any cell matches the filter term
  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

  • Generally, the default sort order for tables is set to be first column ascending; however, specific tables may set a different default sort order.
  • Click on any column header arrows to sort by that column
  • Hold down the Shift key and click multiple columns to sort by more than one column. Be sure to set ascending or descending order for a given column before moving on to the next column.

Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References

Filtering

  • Case insensitive filtering will display rows if any text in any cell matches the filter term
  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

  • Generally, the default sort order for tables is set to be first column ascending; however, specific tables may set a different default sort order.
  • Click on any column header arrows to sort by that column
  • Hold down the Shift key and click multiple columns to sort by more than one column. Be sure to set ascending or descending order for a given column before moving on to the next column.

Clinical Trial Phase Therapies Title Recruitment Status Covered Countries Other Countries
NCT03448042 Phase I BTRC 4017A A Study of Runimotamab in Participants With Locally Advanced or Metastatic HER2-Expressing Cancers Active, not recruiting USA | NLD | ITA | GBR | FRA | ESP | DNK | CAN | BEL | AUS 4


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