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Therapy Name Botensilimab
Synonyms
Therapy Description

Botensilimab (AGEN1181) is an antibody that targets CTLA4, potentially resulting in increased anti-tumor immune response (Journal for ImmunoTherapy of Cancer 2021;9).

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Drug Name Trade Name Synonyms Drug Classes Drug Description
Botensilimab AGEN1181|AGEN 1181|AGEN-1181 CTLA4 Antibody 31 Immune Checkpoint Inhibitor 149 Botensilimab (AGEN1181) is an antibody that targets CTLA4, potentially resulting in increased anti-tumor immune response (Journal for ImmunoTherapy of Cancer 2021;9).

Filtering

  • Case insensitive filtering will display rows if any text in any cell matches the filter term
  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

  • Generally, the default sort order for tables is set to be first column ascending; however, specific tables may set a different default sort order.
  • Click on any column header arrows to sort by that column
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Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References

Filtering

  • Case insensitive filtering will display rows if any text in any cell matches the filter term
  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

  • Generally, the default sort order for tables is set to be first column ascending; however, specific tables may set a different default sort order.
  • Click on any column header arrows to sort by that column
  • Hold down the Shift key and click multiple columns to sort by more than one column. Be sure to set ascending or descending order for a given column before moving on to the next column.

Clinical Trial Phase Therapies Title Recruitment Status Covered Countries Other Countries
NCT03860272 Phase I Botensilimab Fc-Engineered Anti-CTLA-4 Monoclonal Antibody in Advanced Cancer Recruiting USA | GBR 0
NCT05608044 Phase II Balstilimab + Botensilimab Botensilimab A Study of Botensilimab and Balstilimab for the Treatment of Colorectal Cancer Active, not recruiting USA | ITA | FRA | ESP | BRA | BEL 2
NCT05529316 Phase II Botensilimab A Study of Botensilimab (AGEN1181) for the Treatment of Advanced Melanoma Suspended USA | ITA | GBR | FRA | ESP | DEU | CHE | BRA | BEL 1


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