Therapy Detail
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| Therapy Name | Atorvastatin |
| Synonyms | |
| Therapy Description |
Lipitor (atorvastatin) may inhibit farnesylation and geranylgeranylation of small GTP-binding proteins, potentially causing cell cycle arrest in tumor cells (PMID: 31397499). |
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| Drug Name | Trade Name | Synonyms | Drug Classes | Drug Description |
|---|---|---|---|---|
| Atorvastatin | Lipitor | Atogal | Lipitor (atorvastatin) may inhibit farnesylation and geranylgeranylation of small GTP-binding proteins, potentially causing cell cycle arrest in tumor cells (PMID: 31397499). |
Filtering
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- Use simple literal full or partial string matches
- Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
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- Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")
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| Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
|---|
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| Clinical Trial | Phase | Therapies | Title | Recruitment Status | Covered Countries | Other Countries |
|---|---|---|---|---|---|---|
| NCT06157099 | Phase II | Atorvastatin | Atorvastatin for Preventing Disease Metastasis in Patients With Resected High-Risk Stage IIA, IIB, or IIIA Melanoma | Recruiting | USA | 0 |
| NCT04601116 | Phase III | Atorvastatin | The MASTER Study (MAmmary Cancer STatin ER Positive Study) | Recruiting | DNK | 0 |
| NCT03819101 | Phase III | Atorvastatin Aspirin + Atorvastatin Aspirin | Trial of Acetylsalicylic Acid and Atorvastatin in Patients With Castrate-resistant Prostate Cancer (PEACE-4) | Recruiting | FRA | CHE | 0 |
| NCT03560882 | Phase I | Atorvastatin | A Pilot Trial of Atorvastatin in Tumor Protein 53 (p53) -Mutant and p53 Wild-Type Malignancies | Active, not recruiting | USA | 0 |
| NCT04026230 | Phase III | Atorvastatin | Impact of Atorvastatin on Prostate Cancer Progression During ADT (ESTO2) | Recruiting | NOR | FIN | EST | DNK | 0 |
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