Therapy Detail
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| Therapy Name | 177Lu-edotreotide |
| Synonyms | |
| Therapy Description |
177Lu-edotreotide is a radioconjugate comprising the somatostatin analog edotreotide linked to Lu 177, which may have anti-tumor activity (NCI Drug Dictionary). |
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| Drug Name | Trade Name | Synonyms | Drug Classes | Drug Description |
|---|---|---|---|---|
| 177Lu-edotreotide | 177LuDOTATOC|177Lu-DOTA-Tyr3-octreotide|177Lu-Edo | 177Lu-edotreotide is a radioconjugate comprising the somatostatin analog edotreotide linked to Lu 177, which may have anti-tumor activity (NCI Drug Dictionary). |
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| Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
|---|
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| Clinical Trial | Phase | Therapies | Title | Recruitment Status | Covered Countries | Other Countries |
|---|---|---|---|---|---|---|
| NCT03049189 | Phase III | 177Lu-edotreotide Everolimus | Efficacy and Safety of 177Lu-edotreotide PRRT in GEP-NET Patients (COMPETE) | Active, not recruiting | USA | POL | NLD | ITA | GBR | FRA | ESP | DEU | CZE | CHE | BEL | AUT | AUS | 1 |
| NCT04919226 | Phase III | Fluorouracil + Leucovorin + Oxaliplatin 177Lu-edotreotide Everolimus Capecitabine + Temozolomide | Lutetium 177Lu-Edotreotide Versus Best Standard of Care in Well-differentiated Aggressive Grade-2 and Grade-3 GastroEnteroPancreatic NeuroEndocrine Tumors (GEP-NETs) - COMPOSE (COMPOSE) | Active, not recruiting | USA | NLD | ITA | GBR | FRA | ESP | DEU | AUS | 2 |
| NCT05918302 | Phase III | 177Lu-edotreotide Everolimus | Efficacy and Safety of Radiotherapy Compared to Everolimus in Somatostatin Receptor Positive Neuroendocrine Tumors of the Lung and Thymus. (LEVEL) | Recruiting | ITA | FRA | ESP | BEL | 0 |
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