Therapy Detail
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| Therapy Name | AOH1160 + Cisplatin |
| Synonyms | |
| Therapy Description | |
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| Drug Name | Trade Name | Synonyms | Drug Classes | Drug Description |
|---|---|---|---|---|
| AOH1160 | AOH1160 is a small molecule inhibitor that specifically targets cancer associated PCNA (caPCNA) and binds to the region between L126 and Y133, thereby interfering with elongation of the replication fork, and subsequently leading to cell cycle arrest, apoptosis, and tumor growth inhibition (PMID: 29967249). | |||
| Cisplatin | Platinol | CDDP | Chemotherapy - Platinum 7 | Platinol (cisplatin) is a platinum based chemotherapeutic, which is FDA approved for bladder, ovarian, and testicular cancers (NCI Drug Dictionary). |
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| Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
|---|
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| Clinical Trial | Phase | Therapies | Title | Recruitment Status | Covered Countries | Other Countries |
|---|
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