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ID | DOID:3074 |
Name | giant cell glioblastoma |
Definition | A glioblastoma that is characterized by a prevalence of bizarre, multinucleated giant cells. |
Source | DiseaseOntology.org |
Alt Ids | |
Path | disease disease of cellular proliferation cancer cell type cancer high grade glioma malignant astrocytoma glioblastoma giant cell glioblastoma |
Molecular Profile | Therapy | Indication/Tumor Type | Response Type | Profile Response Detail |
---|---|---|---|---|
TSC2 R611W | Everolimus | giant cell glioblastoma | predicted - sensitive | detail... |
Clinical Trial | Phase | Therapies | Title | Recruitment Status | Covered Countries | Other Countries |
---|---|---|---|---|---|---|
NCT01730950 | Phase II | Bevacizumab | Bevacizumab With or Without Radiation Therapy in Treating Patients With Recurrent Glioblastoma | Completed | USA | 0 |
NCT02078648 | Phase Ib/II | SL-701 Poly ICLC Bevacizumab | Safety and Efficacy Study of SL-701, a Glioma-Associated Antigen Vaccine To Treat Recurrent Glioblastoma Multiforme | Completed | USA | 0 |
NCT02287428 | Phase I | NeoVax Pembrolizumab Temozolomide NeoVax + Pembrolizumab + Temozolomide NeoVax + Pembrolizumab | Personalized NeoAntigen Cancer Vaccine w RT Plus Pembrolizumab for Patients With MGMT Unmethylated, Newly Diagnosed GBM | Recruiting | USA | 0 |
NCT02743078 | Phase II | Bevacizumab | Optune Plus Bevacizumab in Bevacizumab-Refractory Recurrent Glioblastoma | Terminated | USA | 0 |
NCT03714334 | Phase I | DNX-2440 | DNX-2440 Oncolytic Adenovirus for Recurrent Glioblastoma | Terminated | ESP | 0 |
NCT03911388 | Phase I | HSV-1 G207 | HSV G207 in Children With Recurrent or Refractory Cerebellar Brain Tumors | Active, not recruiting | USA | 0 |
NCT04482933 | Phase II | HSV-1 G207 | HSV G207 With a Single Radiation Dose in Children With Recurrent High-Grade Glioma | Recruiting | USA | 0 |
NCT06297512 | Phase II | Doxorubicin + Temozolomide | Evaluate the Role of Anthracycline After Radio Therapy in Patients With Glioblastoma (pGBM). | Recruiting | ITA | 0 |
NCT06501911 | Phase I | Bicalutamide | A Study of Bicalutamide With Brain Re-irradiation to Treat Recurrent/Progressive High Grade Glioma | Not yet recruiting | USA | 0 |