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ID DOID:4464
Name collecting duct carcinoma
Definition A renal cell carcinoma that begins in distal collecting ducts of the kidney with a tubulopapillary morphology and intracytoplasmic mucicarminophilic material.
Source DiseaseOntology.org
Alt Ids
Path disease disease of cellular proliferation cancer organ system cancer urinary system cancer kidney cancer renal carcinoma renal cell carcinoma collecting duct carcinoma

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Molecular Profile Therapy Indication/Tumor Type Response Type Profile Response Detail
ATM negative Elimusertib collecting duct carcinoma predicted - sensitive detail...
BRAF G466A Dabrafenib + Trametinib collecting duct carcinoma predicted - sensitive detail...
Clinical Trial Phase Therapies Title Recruitment Status Covered Countries Other Countries
NCT02601937 Phase I Tazemetostat A Phase 1 Study of the EZH2 Inhibitor Tazemetostat in Pediatric Subjects With Relapsed or Refractory INI1-Negative Tumors or Synovial Sarcoma Completed USA | NLD | ITA | GBR | FRA | DNK | DEU | CAN | AUS 0
NCT02601950 Phase II Tazemetostat A Study of Tazemetostat in Adult Participants With Soft Tissue Sarcoma Completed USA | ITA | GBR | FRA | DEU | CAN | BEL | AUS 1
NCT02915783 Phase II Everolimus + Lenvatinib A Phase 2 Trial to Evaluate Efficacy and Safety of Lenvatinib in Combination With Everolimus in Subjects With Unresectable Advanced or Metastatic Non Clear Cell Renal Cell Carcinoma (nccRCC) Who Have Not Received Any Chemotherapy for Advanced Disease Completed USA 0
NCT03587662 Phase II Gemcitabine + Ixazomib Doxorubicin + Gemcitabine + Ixazomib Ixazomib, Gemcitabine, and Doxorubicin in Treating Patients With Locally Advanced or Metastatic Kidney Cancer Active, not recruiting USA 0
NCT03866382 Phase II Cabozantinib + Nivolumab Cabozantinib + Ipilimumab + Nivolumab Cabozantinib in Combination With Nivolumab and Ipilimumab in Rare Genitourinary Tumors Recruiting USA 1
NCT04071223 Phase II Cabozantinib + Radium Ra 223 dichloride Cabozantinib Testing the Addition of a New Anti-cancer Drug, Radium-223 Dichloride, to the Usual Treatment (Cabozantinib) for Advanced Renal Cell Cancer That Has Spread to the Bone, the RadiCaL Study Recruiting USA 0
NCT04413123 Phase II Cabozantinib + Ipilimumab + Nivolumab Cabozantinib In Combo With NIVO + IPI In Advanced NCCRCC Recruiting USA 0
NCT05286801 Phase Ib/II Atezolizumab + Tiragolumab Tiragolumab and Atezolizumab for the Treatment of Relapsed or Refractory SMARCB1 or SMARCA4 Deficient Tumors Recruiting USA | CAN | AUS 0
NCT05347212 Phase II Nivolumab + Relatlimab Phase II Trial of Immunotherapy in Patients With Carcinomas Arising From the Renal Medulla Active, not recruiting USA 0
NCT06302569 Phase II Enfortumab vedotin-ejfv + Pembrolizumab Pembrolizumab Plus Enfortumab Vedotin in Collecting Duct and Renal Medullary Carcinoma (REPRINT) Not yet recruiting ITA 0
NCT06444880 Phase II Cemiplimab + REGN4018 REGN4018 Phase II Trial of Ubamatamab Alone or in Combination With Cemiplimab in MUC16-Expressing SMARCB1-Deficient Malignancies Recruiting USA 0