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| ID | DOID:0081081 |
| Name | acute promyelocytic leukemia with PML-RARA |
| Definition | An acute promyelocytic leukemia that is characterized by a severe coagulopathy and the t(15;17)(q24;q21), generating a PML-RARA fusion gene, and where abnormal promyelocytes predominate. |
| Source | DiseaseOntology.org |
| Alt Ids | |
| Xrefs |
ICDO:9866/3
|
| Path | disease disease of cellular proliferation cancer organ system cancer hematologic cancer leukemia myeloid leukemia acute myeloid leukemia acute promyelocytic leukemia acute promyelocytic leukemia with PML-RARA |
| Molecular Profile | Therapy | Indication/Tumor Type | Response Type | Profile Response Detail |
|---|
| Clinical Trial | Phase | Therapies | Title | Recruitment Status | Covered Countries | Other Countries |
|---|---|---|---|---|---|---|
| NCT07504458 | Phase III | Arsenic trioxide + Tretinoin QTX-2101 + Tretinoin | Pivotal Open-label Phase 3 Clinical Study of QTX-2101 in Adult Patients With Acute Promyelocytic Leukemia (QUATRO-APL) | Recruiting | USA | ROU | FRA | ESP | 0 |