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| ID | DOID:8692 |
| Name | myeloid leukemia |
| Definition | A leukemia that is located_in myeloid tissue. |
| Source | DiseaseOntology.org |
| Alt Ids | DOID:8879 DOID:9066 DOID:8910 DOID:8878 DOID:9126 |
| Path | disease disease of cellular proliferation cancer organ system cancer hematologic cancer leukemia myeloid leukemia |
| Molecular Profile | Therapy | Indication/Tumor Type | Response Type | Profile Response Detail |
|---|---|---|---|---|
| JAK2 V617F | Imatinib | myeloid leukemia | resistant | detail... |
| FLT3 exon 14 ins FLT3 N676S | A-419259 | myeloid leukemia | resistant | detail... |
| FLT3 exon 14 ins FLT3 D835Y | A-419259 | myeloid leukemia | resistant | detail... |
| FLT3 exon 14 ins FLT3 F691L | A-419259 | myeloid leukemia | resistant | detail... |
| FLT3 exon 14 ins | A-419259 | myeloid leukemia | sensitive | detail... |
| Clinical Trial | Phase | Therapies | Title | Recruitment Status | Covered Countries | Other Countries |
|---|---|---|---|---|---|---|
| NCT02129101 | Phase I | Azacitidine Sonidegib | Azacitidine and Sonidegib in Treating Patients With Myeloid Malignancies | Completed | USA | 0 |
| NCT03164057 | Phase II | Etoposide Filgrastim Dexrazoxane Daunorubicin Idarubicin Fludarabine Asparaginase Cytarabine Sorafenib Mitoxantrone Decitabine Azacitidine | A Trial of Epigenetic Priming in Patients With Newly Diagnosed Acute Myeloid Leukemia | Active, not recruiting | USA | 0 |
| NCT03214666 | Phase Ib/II | GTB-3550 TriKE | GTB-3550 Tri-Specific Killer Engager (TriKE®) for High Risk Hematological Malignancies | Terminated | USA | 0 |
| NCT04260022 | Phase I | Olverembatinib | Study of HQP1351 in Subjects With Refractory Chronic Myeloid Leukemia (HQP1351CU101) | Recruiting | USA | CAN | 0 |
| NCT04964518 | Phase I | APG-2575 + Azacitidine | A Study of APG-2575 in Combination With Azacitidine in Patients With Acute Myeloid Leukemia (AML) | Unknown status | USA | AUS | 0 |