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ID | DOID:8692 |
Name | myeloid leukemia |
Definition | A leukemia that is located_in myeloid tissue. |
Source | DiseaseOntology.org |
Alt Ids | DOID:8879 DOID:9066 DOID:8910 DOID:8878 DOID:9126 |
Path | disease disease of cellular proliferation cancer organ system cancer hematologic cancer leukemia myeloid leukemia |
Molecular Profile | Therapy | Indication/Tumor Type | Response Type | Profile Response Detail |
---|---|---|---|---|
JAK2 V617F | Imatinib | myeloid leukemia | resistant | detail... |
FLT3 exon 14 ins FLT3 N676S | A-419259 | myeloid leukemia | resistant | detail... |
FLT3 exon 14 ins FLT3 D835Y | A-419259 | myeloid leukemia | resistant | detail... |
FLT3 exon 14 ins FLT3 F691L | A-419259 | myeloid leukemia | resistant | detail... |
FLT3 exon 14 ins | A-419259 | myeloid leukemia | sensitive | detail... |
Clinical Trial | Phase | Therapies | Title | Recruitment Status | Covered Countries | Other Countries |
---|---|---|---|---|---|---|
NCT02129101 | Phase I | Azacitidine Sonidegib | Azacitidine and Sonidegib in Treating Patients With Myeloid Malignancies | Completed | USA | 0 |
NCT03164057 | Phase II | Etoposide Filgrastim Dexrazoxane Daunorubicin Idarubicin Fludarabine Asparaginase Cytarabine Sorafenib Mitoxantrone Decitabine Azacitidine | A Trial of Epigenetic Priming in Patients With Newly Diagnosed Acute Myeloid Leukemia | Active, not recruiting | USA | 0 |
NCT03214666 | Phase Ib/II | GTB-3550 TriKE | GTB-3550 Tri-Specific Killer Engager (TriKE®) for High Risk Hematological Malignancies | Terminated | USA | 0 |
NCT04260022 | Phase I | Olverembatinib | Study of HQP1351 in Subjects With Refractory Chronic Myeloid Leukemia (HQP1351CU101) | Recruiting | USA | 0 |
NCT04964518 | Phase I | APG-2575 + Azacitidine | A Study of APG-2575 in Combination With Azacitidine in Patients With Acute Myeloid Leukemia (AML) | Recruiting | USA | AUS | 0 |