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Drug Name | GEN1042 |
Trade Name | |
Synonyms | BNT 312|BNT-312|BNT312|GEN-1042|GEN 1042 |
Drug Descriptions |
GEN1042 is a bispecifc agonistic antibody that binds to CD40 and TNFRSF9 (CD137; 4-1BB), potentially resulting in increased T cell proliferation and anti-tumor immune response (PMID: 30400822). |
DrugClasses | CD40 Antibody 14 TNFRSF9 Antibody 32 |
CAS Registry Number | NA |
NCIT ID | C168604 |
Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
---|---|---|---|
GEN1042 | GEN1042 | 0 | 2 |
GEN1042 + Pembrolizumab | GEN1042 Pembrolizumab | 0 | 1 |