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Drug Name | CC-90010 |
Trade Name | |
Synonyms | CC 90010|CC90010|BMS-986378|BMS 986378|BMS986378 |
Drug Descriptions |
CC-90010 is a reversible, small molecule drug that binds to BD2 (bromodomain 2) of BET proteins and inhibits interaction with acetylated histones, potentially resulting in disrupted expression of genes that promote cell growth, and inhibition of proliferation of tumor cells overexpressing BET proteins (PMID: 32240793). |
DrugClasses | BET Inhibitor (Pan) 32 |
CAS Registry Number | NA |
NCIT ID | C151951 |
Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
---|---|---|---|
CC-90010 | CC-90010 | 0 | 3 |
CC-90010 + Temozolomide | CC-90010 Temozolomide | 0 | 1 |
CC-90010 + Vinorelbine | CC-90010 Vinorelbine | 0 | 1 |