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Drug Name Vinorelbine
Trade Name Navelbine
Synonyms Vinorelbin
Drug Descriptions

Navelbine (vinorelbine) is a tubulin binding alkaloid that inhibits tubulin polymerization, thus inhibiting spindle formation, leading to apoptosis (NCI Drug Dictionary). Navelbine (vinorelbine) is approved for use in NSCLC (FDA.gov).

DrugClasses Antimicrotubule Agent 14
CAS Registry Number 71486-22-1
NCIT ID C1395

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Therapy Name Drugs Efficacy Evidence Clinical Trials
Ado-trastuzumab emtansine + Vinorelbine Ado-trastuzumab emtansine Vinorelbine 0 1
Afatinib + Vinorelbine Afatinib Vinorelbine 0 0
Atezolizumab + Bendamustine + Gemcitabine + Vinorelbine Atezolizumab Bendamustine Gemcitabine Vinorelbine 0 1
Atezolizumab + Cyclophosphamide + Vinorelbine Atezolizumab Cyclophosphamide Vinorelbine 0 0
Atezolizumab + Trastuzumab + Vinorelbine Atezolizumab Trastuzumab Vinorelbine 0 1
Atezolizumab + Vinorelbine Atezolizumab Vinorelbine 0 0
Avelumab + Trastuzumab + Utomilumab + Vinorelbine Avelumab Trastuzumab Utomilumab Vinorelbine 0 1
Avelumab + Trastuzumab + Vinorelbine Avelumab Trastuzumab Vinorelbine 0 1
Bendamustine + Gemcitabine + Vinorelbine Bendamustine Gemcitabine Vinorelbine 0 1
Capecitabine + Cisplatin + Docetaxel + Lapatinib + Trastuzumab + Vinorelbine Capecitabine Cisplatin Docetaxel Lapatinib Trastuzumab Vinorelbine 0 0
Capecitabine + Eribulin + Gemcitabine + Vinorelbine Capecitabine Eribulin Gemcitabine Vinorelbine 0 1
Carboplatin + Cisplatin + Docetaxel + Gemcitabine + Pemetrexed Disodium + Vinorelbine Carboplatin Cisplatin Docetaxel Gemcitabine Pemetrexed Disodium Vinorelbine 0 1
Carboplatin + Cisplatin + Gemcitabine + Pemetrexed Disodium + Vinorelbine Carboplatin Cisplatin Gemcitabine Pemetrexed Disodium Vinorelbine 0 0
Carboplatin + Durvalumab + Vinorelbine Carboplatin Durvalumab Vinorelbine 0 1
Carboplatin + Vinorelbine Carboplatin Vinorelbine 0 1
CC-90010 + Vinorelbine CC-90010 Vinorelbine 0 1
Cetuximab + Cisplatin + Vinorelbine Cetuximab Cisplatin Vinorelbine 0 0
Cisplatin + Dulanermin + Vinorelbine Cisplatin Dulanermin Vinorelbine 0 1
Cisplatin + Durvalumab + Vinorelbine Cisplatin Durvalumab Vinorelbine 0 0
Cisplatin + Veliparib + Vinorelbine Cisplatin Veliparib Vinorelbine 0 0
Cisplatin + Vinorelbine Cisplatin Vinorelbine 0 1
Cyclophosphamide + Ramucirumab + Vinorelbine Cyclophosphamide Ramucirumab Vinorelbine 0 2
Cyclophosphamide + Temsirolimus + Vinorelbine Cyclophosphamide Temsirolimus Vinorelbine 0 0
Cyclophosphamide + Vinorelbine Cyclophosphamide Vinorelbine 0 3
Doxorubicin + Gemcitabine + Pembrolizumab + Vinorelbine Doxorubicin Gemcitabine Pembrolizumab Vinorelbine 0 1
Durvalumab + Gemcitabine + Vinorelbine Durvalumab Gemcitabine Vinorelbine 0 1
Durvalumab + Tremelimumab + Vinorelbine Durvalumab Tremelimumab Vinorelbine 0 1
Erlotinib + Gemcitabine + Vinorelbine Erlotinib Gemcitabine Vinorelbine 0 0
Everolimus + Trastuzumab + Vinorelbine Everolimus Trastuzumab Vinorelbine 0 1
Gemcitabine + Vinorelbine Gemcitabine Vinorelbine 0 1
Inetetamab + Pyrotinib + Vinorelbine Inetetamab Pyrotinib Vinorelbine 0 0
JQ1 + Vinorelbine JQ1 Vinorelbine 0 0
Margetuximab-cmkb + Vinorelbine Margetuximab-cmkb Vinorelbine 0 0
Mocetinostat + Vinorelbine Mocetinostat Vinorelbine 0 1
Neratinib + Vinorelbine Neratinib Vinorelbine 0 0
Nimotuzumab + Vinorelbine Nimotuzumab Vinorelbine 0 1
Pertuzumab + Trastuzumab + Vinorelbine Pertuzumab Trastuzumab Vinorelbine 0 2
Pyrotinib + Vinorelbine Pyrotinib Vinorelbine 0 0
Sorafenib + Vinorelbine Sorafenib Vinorelbine 0 1
Trastuzumab + Tucatinib + Vinorelbine Trastuzumab Tucatinib Vinorelbine 0 2
Trastuzumab + Vinorelbine Trastuzumab Vinorelbine 0 6
Trastuzumab + Vinorelbine + Zenocutuzumab Trastuzumab Vinorelbine Zenocutuzumab 0 1
Vinorelbine Vinorelbine 1 24
Vinorelbine + ZW25 Vinorelbine ZW25 0 2


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