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Drug Name Daromun
Trade Name
Synonyms L19-IL2/L19-TNF-alpha|Darleukin/Fibromun|L19IL2/L19TNF
Drug Descriptions

Daromun consists of a mixture of darleukin, a recombinant IL2 linked to the fibronectin extra domain B (EDB) targeting single-chain variable fragment (L19), and fibromun, a human TNF-alpha linked to L19, which binds to cells expressing fibronectin EDB in tumor neovasculature, potentially resulting in the induction of antitumor immune response against tumor cells expressing EDB-containing fibronectin (NCI Drug Dictionary).

DrugClasses
CAS Registry Number NA
NCIT ID C154627

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Therapy Name Drugs Efficacy Evidence Clinical Trials
Daromun Daromun 0 2
Daromun + Lomustine Daromun Lomustine 0 0
Daromun + Onfekafusp alfa Daromun Onfekafusp alfa 0 1


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