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Drug Name EOS100850
Trade Name
Synonyms EOS-100850|EOS 100850|Inupadenant
Drug Descriptions

EOS100850 is an antagonist that selectively targets the A2A receptor and inhibits downstream signaling, which potentially induces an inflammatory response against tumor cells (Cancer Res 2019;79(13 Suppl):Abstract nr 4147).

DrugClasses Adenosine Targeting 23
CAS Registry Number NA
NCIT ID C172109

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Therapy Name Drugs Efficacy Evidence Clinical Trials
Carboplatin + EOS100850 + Pemetrexed Disodium Carboplatin EOS100850 Pemetrexed Disodium 0 1
EOS-448 + EOS100850 EOS-448 EOS100850 0 1
EOS100850 EOS100850 0 2
EOS100850 + Pembrolizumab EOS100850 Pembrolizumab 0 1
EOS100850 + unspecified CTLA4 antibody EOS100850 unspecified CTLA4 antibody 0 0


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