YM-254890
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| Drug Name | YM-254890 |
| Trade Name | |
| Synonyms | YM254890|YM 254890 |
| Drug Descriptions |
YM-254890 is a specific inhibitor of the G protein-coupled receptor, Gq (PMID: 31539242), that inhibits the exchange reaction of GDP/GTP by inhibiting the release of GDP (PMID: 20639466), and may lead to inhibition of cell proliferation and tumor formation (PMID: 33229459). |
| DrugClasses | |
| CAS Registry Number | 568580-02-9 |
| NCIT ID | NA |
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| Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
|---|---|---|---|
| Alpelisib + YM-254890 | Alpelisib YM-254890 | 0 | 0 |
| AXL1717 + YM-254890 | AXL1717 YM-254890 | 0 | 0 |
| Binimetinib + YM-254890 | Binimetinib YM-254890 | 0 | 0 |
| Linsitinib + YM-254890 | Linsitinib YM-254890 | 0 | 0 |
| Trametinib + YM-254890 | Trametinib YM-254890 | 1 | 0 |
| YM-254890 | YM-254890 | 3 | 0 |
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