Drug Detail

Contact

Missing content? – Request curation!

Request curation for specific Genes, Variants, or PubMed publications.

Have questions, comments, or suggestions? - Let us know!

Email us at : ckbsupport@genomenon.com

Drug Name Linsitinib
Trade Name
Synonyms OSI-906
Drug Descriptions

Linsitinib (OSI-906) is a small molecule dual inhibitor of IGF-1R and IR, which leads to decreased tumor cell proliferation (PMID: 21425998, PMID: 31792037).

DrugClasses IGF-1R Inhibitor 17
CAS Registry Number 867160-71-2
NCIT ID C70982

Filtering

  • Case insensitive filtering will display rows if any text in any cell matches the filter term
  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

  • Generally, the default sort order for tables is set to be first column ascending; however, specific tables may set a different default sort order.
  • Click on any column header arrows to sort by that column
  • Hold down the Shift key and click multiple columns to sort by more than one column. Be sure to set ascending or descending order for a given column before moving on to the next column.

Therapy Name Drugs Efficacy Evidence Clinical Trials
ARS1620 + Everolimus + Linsitinib ARS1620 Everolimus Linsitinib 0 0
ARS1620 + Linsitinib ARS1620 Linsitinib 0 0
AZD8055 + Linsitinib AZD8055 Linsitinib 0 0
AZD8055 + Linsitinib + Trametinib AZD8055 Linsitinib Trametinib 0 0
BLZ945 + Linsitinib BLZ945 Linsitinib 0 0
Bortezomib + Dexamethasone + Linsitinib Bortezomib Dexamethasone Linsitinib 0 1
Crizotinib + Lapatinib + Linsitinib Crizotinib Lapatinib Linsitinib 0 0
Crizotinib + Linsitinib Crizotinib Linsitinib 0 0
Dabrafenib + Linsitinib Dabrafenib Linsitinib 0 0
Erlotinib + Linsitinib Erlotinib Linsitinib 0 0
Everolimus + Linsitinib Everolimus Linsitinib 0 0
Everolimus + Linsitinib + Trametinib Everolimus Linsitinib Trametinib 0 0
Gefitinib + Linsitinib Gefitinib Linsitinib 0 0
Gefitinib + Linsitinib + PHA-665752 Gefitinib Linsitinib PHA-665752 0 0
Linsitinib Linsitinib 0 0
Linsitinib + Midostaurin Linsitinib Midostaurin 0 0
Linsitinib + Palbociclib Linsitinib Palbociclib 0 0
Linsitinib + PF-4708671 Linsitinib PF-4708671 0 0
Linsitinib + Pictilisib Linsitinib Pictilisib 1 0
Linsitinib + Sapanisertib Linsitinib Sapanisertib 0 0
Linsitinib + Sapanisertib + Trametinib Linsitinib Sapanisertib Trametinib 0 0
Linsitinib + SCH772984 Linsitinib SCH772984 0 0
Linsitinib + Selumetinib Linsitinib Selumetinib 0 0
Linsitinib + Temsirolimus Linsitinib Temsirolimus 0 0
Linsitinib + Temsirolimus + Trametinib Linsitinib Temsirolimus Trametinib 0 0
Linsitinib + Temsirolimus + Trastuzumab Linsitinib Temsirolimus Trastuzumab 0 0
Linsitinib + Torkinib Linsitinib Torkinib 0 0
Linsitinib + Torkinib + Trametinib Linsitinib Torkinib Trametinib 0 0
Linsitinib + YM-254890 Linsitinib YM-254890 0 0


Additional content available in CKB BOOST