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Drug Name BI 764532
Trade Name
Synonyms BI-764532|BI764532|Obrixtamig
Drug Descriptions

BI 764532 is a bispecific antibody targeting DLL3 and CD3, which may lead to activation of T-cell-mediated immune response against DLL3-expressing tumor cells (J Clin Oncol 41, 2023 (suppl 16; abstr 8502)).

DrugClasses CD3 Antibody 99 DLL3 Antibody 6
CAS Registry Number 2851943-09-2
NCIT ID C177765

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Therapy Name Drugs Efficacy Evidence Clinical Trials
Atezolizumab + BI 764532 + Carboplatin + Etoposide Atezolizumab BI 764532 Carboplatin Etoposide 0 1
BI 764532 BI 764532 0 4
BI 764532 + Carboplatin + Durvalumab + Etoposide BI 764532 Carboplatin Durvalumab Etoposide 0 1
BI 764532 + Carboplatin + Etoposide BI 764532 Carboplatin Etoposide 0 1
BI 764532 + Cisplatin + Durvalumab + Etoposide BI 764532 Cisplatin Durvalumab Etoposide 0 1
BI 764532 + Cisplatin + Etoposide BI 764532 Cisplatin Etoposide 0 1
BI 764532 + Ezabenlimab BI 764532 Ezabenlimab 0 1
BI 764532 + Topotecan BI 764532 Topotecan 0 1


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