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Drug Name TransCon TLR7/8 Agonist
Trade Name
Synonyms Resiquimod Hydrogel-based Sustained-release formulation
Drug Descriptions

TransCon TLR7/8 Agonist is a hydrogel based formulation of an imidazoquinolinamine and resiquimod, which acts as an agonist of TLR 7 and TLR8, which potentially activates the antitumor immune response and may lead to tumor cell lysis (NCI Drug Dictionary).

DrugClasses TLR7 Agonist 13 TLR8 Agonist 10
CAS Registry Number NA
NCIT ID C179719

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Therapy Name Drugs Efficacy Evidence Clinical Trials
Pembrolizumab + TransCon TLR7/8 Agonist Pembrolizumab TransCon TLR7/8 Agonist 0 2
TransCon IL-2 beta/gamma + TransCon TLR7/8 Agonist TransCon IL-2 beta/gamma TransCon TLR7/8 Agonist 0 1
TransCon TLR7/8 Agonist TransCon TLR7/8 Agonist 0 1


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