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Drug Name TransCon TLR7/8 Agonist
Trade Name
Synonyms Resiquimod Hydrogel-based Sustained-release formulation
Drug Descriptions

TransCon TLR7/8 Agonist is a hydrogel based formulation of an imidazoquinolinamine and resiquimod, which acts as an agonist of TLR 7 and TLR8, which potentially activates the antitumor immune response and may lead to tumor cell lysis (NCI Drug Dictionary).

DrugClasses TLR7 Agonist 12 TLR8 Agonist 9
CAS Registry Number NA
NCIT ID C179719

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Therapy Name Drugs Efficacy Evidence Clinical Trials
Pembrolizumab + TransCon TLR7/8 Agonist Pembrolizumab TransCon TLR7/8 Agonist 0 2
TransCon IL-2 beta/gamma + TransCon TLR7/8 Agonist TransCon IL-2 beta/gamma TransCon TLR7/8 Agonist 0 1
TransCon TLR7/8 Agonist TransCon TLR7/8 Agonist 0 1


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