Drug Detail

Contact

Missing content? – Request curation!

Request curation for specific Genes, Variants, or PubMed publications.

Have questions, comments, or suggestions? - Let us know!

Email us at : ckbsupport@genomenon.com

Drug Name MK-7684A
Trade Name
Synonyms MK-7684/MK-3475|Vibostolimab/Pembrolizumab
Drug Descriptions

MK-7684A is a co-formulation of the immune checkpoint inhibitor Keytruda (pembrolizumab) and MK-7684 (Vibostolimab), an antibody directed against T-cell immunoreceptor with Ig and ITIM domains (TIGIT), which may lead to the activation of immune response against tumor cells (NCI Drug Dictionary).

DrugClasses Immune Checkpoint Inhibitor 149 PD-L1/PD-1 antibody 121 TIGIT Antibody 19
CAS Registry Number NA
NCIT ID C176841

Filtering

  • Case insensitive filtering will display rows if any text in any cell matches the filter term
  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

  • Generally, the default sort order for tables is set to be first column ascending; however, specific tables may set a different default sort order.
  • Click on any column header arrows to sort by that column
  • Hold down the Shift key and click multiple columns to sort by more than one column. Be sure to set ascending or descending order for a given column before moving on to the next column.

Therapy Name Drugs Efficacy Evidence Clinical Trials
Carboplatin + Etoposide + MK-7684A Carboplatin Etoposide MK-7684A 0 1
Carboplatin + MK-7684A + Nab-paclitaxel Carboplatin MK-7684A Nab-paclitaxel 0 1
Carboplatin + MK-7684A + Paclitaxel Carboplatin MK-7684A Paclitaxel 0 2
Carboplatin + MK-7684A + Pemetrexed Disodium Carboplatin MK-7684A Pemetrexed Disodium 0 1
Cisplatin + Etoposide + MK-7684A Cisplatin Etoposide MK-7684A 0 2
Cisplatin + Fluorouracil + MK-7684A Cisplatin Fluorouracil MK-7684A 0 1
Cisplatin + MK-7684A + Pemetrexed Disodium Cisplatin MK-7684A Pemetrexed Disodium 0 2
Docetaxel + MK-7684A Docetaxel MK-7684A 0 1
Enfortumab vedotin-ejfv + MK-7684A Enfortumab vedotin-ejfv MK-7684A 0 1
Lenvatinib + MK-7684A Lenvatinib MK-7684A 0 1
MK-7684A MK-7684A 0 7
MK-7684A + Paclitaxel MK-7684A Paclitaxel 0 1


Additional content available in CKB BOOST