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Drug Name RO7227166
Trade Name
Synonyms RO 7227166|RO-7227166|Ensomafusp Alfa|RG6076|RG-6076|RG 6076|Englumafusp Alfa
Drug Descriptions

RO7227166 is a bispecific antibody that targets both CD19 and TNFRSF9 (4-1BB), potentially resulting in enhanced anti-tumor immune response (Blood (2022) 140 (Supplement 1): 9461-9463).

DrugClasses CD19 Antibody 21 TNFRSF9 Antibody 32
CAS Registry Number NA
NCIT ID C169052

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Therapy Name Drugs Efficacy Evidence Clinical Trials
Glofitamab-gxbm + Obinutuzumab + RO7227166 + Tocilizumab Glofitamab-gxbm Obinutuzumab RO7227166 Tocilizumab 0 1
Glofitamab-gxbm + RO7227166 Glofitamab-gxbm RO7227166 0 0
Obinutuzumab + RO7227166 + Tocilizumab Obinutuzumab RO7227166 Tocilizumab 0 1
RO7227166 RO7227166 0 0


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