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Drug Name Tocilizumab
Trade Name Actemra
Synonyms Atlizumab
Drug Descriptions

Actemra (tocilizumab) is a humamized monoclonal antibody that targets IL-6R, resulting in decreased downstream signaling and potentially resulted in decreased tumor growth and progression (PMID: 26751841, PMID: 25658637). Actemra (tocilizumab) is FDA approved for use in treating rheumatoid arthritis, polyarticular juvenile idiopathic arthritis, and systemic juvenile idiopathic arthritis (FDA.gov).

DrugClasses
CAS Registry Number 375823-41-9
NCIT ID C84217

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Therapy Name Drugs Efficacy Evidence Clinical Trials
Atezolizumab + Bevacizumab + Tocilizumab Atezolizumab Bevacizumab Tocilizumab 0 1
Atezolizumab + Glofitamab-gxbm + Obinutuzumab + Tocilizumab Atezolizumab Glofitamab-gxbm Obinutuzumab Tocilizumab 0 1
Atezolizumab + Mosunetuzumab-axgb + Tiragolumab + Tocilizumab Atezolizumab Mosunetuzumab-axgb Tiragolumab Tocilizumab 0 1
Atezolizumab + Tocilizumab Atezolizumab Tocilizumab 0 3
Carboplatin + Etoposide + Glofitamab-gxbm + Ifosfamide + Obinutuzumab + Rituximab + Tocilizumab Carboplatin Etoposide Glofitamab-gxbm Ifosfamide Obinutuzumab Rituximab Tocilizumab 0 1
Carboplatin + Tocilizumab Carboplatin Tocilizumab 0 1
CC-1 + Tocilizumab CC-1 Tocilizumab 0 1
Cevostamab + Lenalidomide + Tocilizumab Cevostamab Lenalidomide Tocilizumab 0 1
Cevostamab + RO7310729 + Tocilizumab Cevostamab RO7310729 Tocilizumab 0 1
Cevostamab + Tocilizumab Cevostamab Tocilizumab 0 3
Dasatinib + RO7283420 + Tocilizumab Dasatinib RO7283420 Tocilizumab 0 1
Glofitamab-gxbm + Obinutuzumab + Polatuzumab vedotin-piiq + Tocilizumab Glofitamab-gxbm Obinutuzumab Polatuzumab vedotin-piiq Tocilizumab 0 1
Glofitamab-gxbm + Obinutuzumab + RO7227166 + Tocilizumab Glofitamab-gxbm Obinutuzumab RO7227166 Tocilizumab 0 1
Glofitamab-gxbm + Obinutuzumab + RO7443904 + Tocilizumab Glofitamab-gxbm Obinutuzumab RO7443904 Tocilizumab 0 1
Glofitamab-gxbm + Obinutuzumab + Tocilizumab Glofitamab-gxbm Obinutuzumab Tocilizumab 0 1
Glofitamab-gxbm + RO7443904 + Tocilizumab Glofitamab-gxbm RO7443904 Tocilizumab 0 0
Ipilimumab + Nivolumab + Tocilizumab Ipilimumab Nivolumab Tocilizumab 0 2
Lenalidomide + Mosunetuzumab-axgb + Tocilizumab Lenalidomide Mosunetuzumab-axgb Tocilizumab 0 1
Lenalidomide + Rituximab + Tocilizumab Lenalidomide Rituximab Tocilizumab 0 1
Mosunetuzumab-axgb + Polatuzumab vedotin-piiq + Tocilizumab Mosunetuzumab-axgb Polatuzumab vedotin-piiq Tocilizumab 0 1
Mosunetuzumab-axgb + Tiragolumab + Tocilizumab Mosunetuzumab-axgb Tiragolumab Tocilizumab 0 1
Mosunetuzumab-axgb + Tocilizumab Mosunetuzumab-axgb Tocilizumab 0 3
Nivolumab + Tocilizumab Nivolumab Tocilizumab 0 1
Obinutuzumab + RO7227166 + Tocilizumab Obinutuzumab RO7227166 Tocilizumab 0 1
Obinutuzumab + RO7293583 + Tocilizumab Obinutuzumab RO7293583 Tocilizumab 0 1
Obinutuzumab + Tocilizumab Obinutuzumab Tocilizumab 0 0
Pertuzumab + Tocilizumab + Trastuzumab Pertuzumab Tocilizumab Trastuzumab 0 1
RO7119929 + Tocilizumab RO7119929 Tocilizumab 0 1
RO7293583 + Tocilizumab RO7293583 Tocilizumab 0 1
RO7444973 + Tocilizumab RO7444973 Tocilizumab 0 1
RO7515629 + Tocilizumab RO7515629 Tocilizumab 0 0
RO7616789 + Tocilizumab RO7616789 Tocilizumab 0 0
RO7617991 + Tocilizumab RO7617991 Tocilizumab 0 1
SAIL66 + Tocilizumab SAIL66 Tocilizumab 0 1
Teclistamab + Tocilizumab Teclistamab Tocilizumab 0 1
Tocilizumab Tocilizumab 0 14
Tocilizumab + Venetoclax Tocilizumab Venetoclax 0 1


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