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Drug Name | Pegcetacoplan |
Trade Name | |
Synonyms | APL2|APL-2|APL 2 |
Drug Descriptions |
Pegcetacoplan binds to and inhibits C3 and C3b, resulting in decreased activation of the complement pathway and potentially leading to reduced inflammation and cell lysis (PMID: 33464651, NCI Drug Dictionary) |
DrugClasses | |
CAS Registry Number | NA |
NCIT ID | C170296 |
Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
---|---|---|---|
Bevacizumab + Pegcetacoplan + Pembrolizumab | Bevacizumab Pegcetacoplan Pembrolizumab | 0 | 1 |
Pegcetacoplan | Pegcetacoplan | 0 | 0 |
Pegcetacoplan + Pembrolizumab | Pegcetacoplan Pembrolizumab | 0 | 1 |