Pegcetacoplan
Drug Detail
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| Drug Name | Pegcetacoplan |
| Trade Name | |
| Synonyms | APL2|APL-2|APL 2 |
| Drug Descriptions |
Pegcetacoplan binds to and inhibits C3 and C3b, resulting in decreased activation of the complement pathway and potentially leading to reduced inflammation and cell lysis (PMID: 33464651, NCI Drug Dictionary) |
| DrugClasses | |
| CAS Registry Number | NA |
| NCIT ID | C170296 |
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| Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
|---|---|---|---|
| Bevacizumab + Pegcetacoplan + Pembrolizumab | Bevacizumab Pegcetacoplan Pembrolizumab | 0 | 1 |
| Fluorouracil + Irinotecan + Leucovorin + Oxaliplatin + Pegcetacoplan | Fluorouracil Irinotecan Leucovorin Oxaliplatin Pegcetacoplan | 0 | 1 |
| Pegcetacoplan | Pegcetacoplan | 0 | 0 |
| Pegcetacoplan + Pembrolizumab | Pegcetacoplan Pembrolizumab | 0 | 1 |
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