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Drug Name | KN046 |
Trade Name | |
Synonyms | KN 046|KN-046|Erfonrilimab |
Drug Descriptions |
KN046 is a bispecific monoclonal antibody that targets PD-L1 (CD274) expressed on tumor cells and CTLA-4 on T lymphocytes, potentially leading to enhanced antitumor immune response (PMID: 37263673). |
DrugClasses | CTLA4 Antibody 31 Immune Checkpoint Inhibitor 149 PD-L1/PD-1 antibody 121 |
CAS Registry Number | 2367013-69-0 |
NCIT ID | C157632 |
Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
---|---|---|---|
Cisplatin + KN046 + Paclitaxel | Cisplatin KN046 Paclitaxel | 0 | 0 |
Gemcitabine + KN046 + Nab-paclitaxel | Gemcitabine KN046 Nab-paclitaxel | 0 | 0 |
KN046 | KN046 | 0 | 1 |
KN046 + Lenvatinib | KN046 Lenvatinib | 0 | 0 |