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Drug Name | OH2 |
Trade Name | |
Synonyms | OH-2|OH 2|oHSV-2-expressing GM-CSF OH2 |
Drug Descriptions |
OH2 is an oncolytic herpes simplex virus-2 (HSV-2) engineered to include deletions in the viral genes ICP34.5 and ICP47, and to express human granulocyte macrophage colony stimulating factor (GM-CSF), which may lead to the activation of anti-tumor immune response and tumor cell killing (PMID: 32055679, PMID: 29872496). |
DrugClasses | |
CAS Registry Number | NA |
NCIT ID | C172106 |
Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
---|---|---|---|
HX008 + OH2 | HX008 OH2 | 0 | 0 |
OH2 | OH2 | 0 | 0 |