ABBV-514
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| Drug Name | ABBV-514 |
| Trade Name | |
| Synonyms | ABBV514|ABBV 514 |
| Drug Descriptions |
ABBV-514 is an afucosylated antibody targeting CCR8, which potentially induces antibody-dependent cellular cytotoxicity (ADCC) and depletion of CCR8-positive regulatory T-cells (Cancer Res (2025) 85 (8_Supplement_1): 6025). |
| DrugClasses | CCR8 Antibody 13 |
| CAS Registry Number | NA |
| NCIT ID | C213671 |
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| Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
|---|---|---|---|
| ABBV-514 | ABBV-514 | 0 | 1 |
| ABBV-514 + Bevacizumab | ABBV-514 Bevacizumab | 0 | 1 |
| ABBV-514 + Budigalimab | ABBV-514 Budigalimab | 0 | 1 |
| ABBV-514 + Pembrolizumab | ABBV-514 Pembrolizumab | 0 | 0 |
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