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Drug Name | ACT001 |
Trade Name | |
Synonyms | ACT-001|ACT 001 |
Drug Descriptions |
ACT001 binds to SERPINE1 (PAI-1) and inhibits PI3K/AKT pathway signaling, potentially leading to inhibition of tumor cell proliferation and migration and decreased tumor growth (PMID: 31591377). |
DrugClasses | |
CAS Registry Number | NA |
NCIT ID | C182143 |
Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
---|---|---|---|
ACT001 | ACT001 | 0 | 1 |
ACT001 + Cisplatin | ACT001 Cisplatin | 0 | 0 |
ACT001 + Pembrolizumab | ACT001 Pembrolizumab | 0 | 1 |