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Drug Name NUV-868
Trade Name
Synonyms NUV868|NUV 868
Drug Descriptions

NUV-868 selectively binds to the BD2 domain of the BRD4 protein, leading to disruption of chromatin remodeling and decreased expression of oncogenes, potentially leading to growth inhibition of tumor cells (NCI Drug Dictionary).

DrugClasses BET Inhibitor (Pan) 32
CAS Registry Number NA
NCIT ID C187038

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Therapy Name Drugs Efficacy Evidence Clinical Trials
Enzalutamide + NUV-868 Enzalutamide NUV-868 0 1
NUV-868 NUV-868 0 1
NUV-868 + Olaparib NUV-868 Olaparib 0 1


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