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Drug Name | NUV-868 |
Trade Name | |
Synonyms | NUV868|NUV 868 |
Drug Descriptions |
NUV-868 selectively binds to the BD2 domain of the BRD4 protein, leading to disruption of chromatin remodeling and decreased expression of oncogenes, potentially leading to growth inhibition of tumor cells (NCI Drug Dictionary). |
DrugClasses | BET Inhibitor (Pan) 32 |
CAS Registry Number | NA |
NCIT ID | C187038 |
Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
---|---|---|---|
Enzalutamide + NUV-868 | Enzalutamide NUV-868 | 0 | 1 |
NUV-868 | NUV-868 | 0 | 1 |
NUV-868 + Olaparib | NUV-868 Olaparib | 0 | 1 |