MVC-101
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| Drug Name | MVC-101 |
| Trade Name | |
| Synonyms | MVC 101|MVC101|TAK 186|TAK-186|TAK186 |
| Drug Descriptions |
MVC-101 is a bispecific T cell engager that targets EGFR expressed on tumor cells and CD3 antigen found on T cells, which upon proteolytic cleavage of the linker potentially leads to T cell activation against tumor cells and subsequent tumor regression (PMID: 32684124). |
| DrugClasses | CD3 Antibody 119 EGFR Antibody 72 |
| CAS Registry Number | NA |
| NCIT ID | C180595 |
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| Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
|---|---|---|---|
| MVC-101 | MVC-101 | 0 | 1 |
| MVC-101 + Nivolumab | MVC-101 Nivolumab | 0 | 1 |
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